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Updated: Jun 11, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

増強されたデンドリット細胞抗原捕獲は,トール型受容体誘発アクチンリモデリングによるものです

Michele A West1, Robert P A Wallin, Stephen P Matthews

  • 1Division of Cell Biology and Immunology, Wellcome Trust Biocentre, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.

Science (New York, N.Y.)
|August 25, 2004
PubMed
まとめ

トール型受容体 (TLR) リガンドは,最初,アクチン細胞骨格を動員することによって,デンドリット細胞 (DC) の抗原の吸収とプレゼンテーションを刺激します. この一時的な反応はT細胞の活性化を高め,DC成熟に関する以前の概念に異議を唱える.

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