関連する実験動画

Updated: Jul 6, 2026

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton
08:01

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton

Published on: April 19, 2018

ハイドロフォビックコアの再梱包は,ファグディスプレイによるコイル・コイル・ダイマー:タンパク質-タンパク質インターフェースにおける可塑性および特異性に関する洞察

Jonathan R Lai1, John D Fisk, Bernard Weisblum

  • 1Graduate Program in Biophysics, University of Wisconsin, Madison, Wisconsin 53706, USA.

Journal of the American Chemical Society
|August 26, 2004
PubMed
まとめ

この研究は,水害性コアにおけるステリックマッチングが,コイル-コイルタンパク質の相互作用を駆動することを明らかにしています. ファージディスプレイは,新しいヘテロジマーペアを特定し,タンパク質の特異性と設計に関する洞察を提供しました.

さらに関連する動画

Three-dimensional Imaging of Bacterial Cells for Accurate Cellular Representations and Precise Protein Localization06:33

Three-dimensional Imaging of Bacterial Cells for Accurate Cellular Representations and Precise Protein Localization

Published on: October 29, 2019

C. elegans Gonad Dissection and Freeze Crack for Immunofluorescence and DAPI Staining06:04

C. elegans Gonad Dissection and Freeze Crack for Immunofluorescence and DAPI Staining

Published on: September 16, 2022

関連する概念動画

Protein Folding01:22

Protein Folding

Overview
DNA Packaging00:58

DNA Packaging

Overview
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Bacterial Protein Maturation01:26

Bacterial Protein Maturation

Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...