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Updated: Jul 15, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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1,5-エニンの触媒性イソメリゼーションにより,ビサイクロ[3.1.0]ヘキセンスをバイサイクロ[3.1.0]ヘキセンスを生成する

Michael R Luzung1, Jordan P Markham, F Dean Toste

  • 1Center for New Directions in Organic Synthesis, Department of Chemistry, University of California-Berkeley, Berkeley, CA 94720, USA.

Journal of the American Chemical Society
|September 2, 2004
PubMed
まとめ

金 (((I) 触媒は,1,5-エニンのサイクロアイソメリゼーションを容易にし,ビサイクロ[3.1.0]ヘクセンの生成を促進します. この反応は多様な置換を許容し,優れたステレオ特異性およびキラリティ移転を達成し,複雑な分子合成を可能にします.

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