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Updated: Jul 14, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

CD8β鎖の免疫学的役割について

C J Wheeler1, P von Hoegen, J R Parnes

  • 1Department of Medicine, Stanford University Medical Center, California 94305.

Nature
|May 21, 1992
PubMed
まとめ

CD8ベータ鎖は,アルファ鎖だけでなく,T細胞の反応において重要な役割を果たします. この研究では,CD8αβヘテロダイマーがインタールイキン-2の産生を増加させ,CD8β成分に特異的な機能があることを示唆しています.

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Overview
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Immune Surveillance by NK Cells and Phagocytes

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Antigens Involved in Adaptive Immunity

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Complete Antigens
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T Cell Activation and Clonal Selection

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Cytotoxic T Cells-mediated Immune Response

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