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Updated: Jul 25, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

脊髄チオエステル交換:ポリペプチドの高位構造安定性を評価するための新しいアプローチ

Matthew G Woll1, Samuel H Gellman

  • 1Department of Chemistry, University of Wisconsin--Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.

Journal of the American Chemical Society
|September 10, 2004
PubMed
まとめ

研究者らは,牛の臓ポリペプチド (bPP) のアミド結合を動的チオエステルで置き換えました. これにより,可逆性脊髄チオエステル交換 (BTE) が可能になり,ペプチドの構造的安定性および非共性相互作用に関する研究が可能になります.

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Protein Organization01:13

Protein Organization

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Protein Folding01:22

Protein Folding

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Protein and Protein Structure

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A protein's shape is critical to its function. For example, an enzyme can...
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For example, in...
Protein Organization01:24

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Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
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