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Updated: Jan 10, 2026

Bacterial Phylum Spirochaetes
01:30

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Published on: June 12, 2025

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mdm-2腫瘍遺伝子の製品は,p53タンパク質と複合体を形成し,p53-媒介トランザクティベーションを阻害する

J Momand1, G P Zambetti, D C Olson

  • 1Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, New Jersey 08544-1014.

Cell
|June 26, 1992
PubMed
まとめ

マウリン双分2 (mdm-2) 腫瘍遺伝子の製品は,p53タンパク質に結合する. この相互作用はp53の腫瘍抑制活性を抑制し,細胞の腫瘍発生の可能性に影響を与えます.

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