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Updated: Aug 9, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
11:51

Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

フェニルケトンウリアにおけるテトラヒドロアイソキノリンの蓄積

J M Lasala, C J Coscia

    Science (New York, N.Y.)
    |January 19, 1979
    PubMed
    まとめ

    3',4'-デオキシノラウダノソリンカルボキシル酸 (DNLCA) は,フェニルケトンウリンの子どもとハイパーフェニラララニネミックのラットで発見されました. このテトラヒドロアイソキノリンは,ドーパミンβ-ヒドロキシラーゼの阻害体であり,脳,特に小脳と皮質に蓄積されます.

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