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Updated: Mar 30, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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BAFF依存のPKCデルタ媒介核信号によるB細胞生存の調節

Ingrid Mecklenbräuker1, Susan L Kalled, Michael Leitges

  • 1Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA.

Nature
|September 14, 2004
PubMed
まとめ

科学者たちは,身体がB細胞の生存を制御する新しい方法を発見しました. タンパク質キナーゼCdelta (PKCdelta) は通常,B細胞死を誘発しますが,BAFFはこれを防止し,潜在的に自己免疫疾患に影響を与えます.

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