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左心室の適合性に対する老化と身体活動の影響
Armin Arbab-Zadeh1, Erika Dijk, Anand Prasad
1Institute for Exercise and Environmental Medicine, Presbyterian Hospital, and University of Texas Southwestern Medical Center, Dallas, Tex 75231, USA.
Circulation
|September 15, 2004
まとめ
静止型老化は,左心室の適合性を著しく低下させ,ダイアストリック機能に影響を及ぼします. しかし,耐久力トレーニングは,この重要な心臓機能を保ち,高齢者の心不全を予防する可能性があります.
科学分野:
- 心臓病学 心臓病学
- ゲロントロジーはゲロントロジーの学科です.
- 運動生理学 運動生理学
背景:
- 老化は,左心室の適合性の低下と関連しており,これは高齢者の心不全の潜在的な要因である.
- この減少が老化によるものなのか,あるいは身体活動の減少によるものなのかは不明である.
研究 の 目的:
- 老化における左心室適合に対するライフスタイルの影響を調査する.
- 静止型高齢者,マスターアスリート,若年成人の心臓機能を比較するために.
主な方法:
- 肺動脈カテーテリゼーションは,スターリングと左心室の圧力-体積曲線を決定するために使用されました.
- 測定には,肺毛細血管のの圧力と左心室の末期ダイアストリック容量が含まれていました.
- 心臓の充填は,下部負圧と塩水注入を用いて操作された.
主要な成果:
- 静止型高齢者は,若い対照群と比較して左心室適合性の低下を示し,心臓の圧力が高くなり,心筋壁のストレスを引き起こす.
- マスターズ選手は左心室の順守が保たれ,圧力-体積の曲線は若年成人と区別がつかない.
- 運動選手の脳卒中量は,静止型高齢者よりも高かったが,収縮性は類似していた.
結論:
- 老化に伴う静止生活は,左心室の適合性の低下と腹動機能不全と関連しています.
- 持続的な耐久力トレーニングは,高齢者の心室適合性を維持します.
- 運動は,高齢者の心不全を予防する鍵となるかもしれません.
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