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Updated: Jul 21, 2026

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
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Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

肥満患者の循環する単核細胞は,炎症を誘発する状態にある

Husam Ghanim1, Ahmad Aljada, Deborah Hofmeyer

  • 1Division of Endocrinology, Diabetes, and Metabolism, State University of New York at Buffalo, NY, USA.

Circulation
|September 15, 2004
PubMed
まとめ

肥満は,外周血液単核細胞 (MNC) の炎症性状態を誘発し,核因子カッパB (NF-kappaB) の活性が増加し,炎症性遺伝子発現が上昇することが特徴です. この炎症はインスリン抵抗性に関連しており,自由脂肪酸 (FFAs) によって調節されます.

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