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Updated: Jul 20, 2026

Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

刺激に反応する,線形-形共ポリマーの超分子組成

Elizabeth R Gillies1, Thomas B Jonsson, Jean M J Fréchet

  • 1Center for New Directions in Organic Synthesis, Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.

Journal of the American Chemical Society
|September 24, 2004
PubMed
まとめ

新しいpH反応性ミセルは,線形-デンドリットブロックコポリマーを使用して開発されました. これらのミセルは,ペイロードをカプセル化し,酸性条件下で放出し,制御された薬物投与システムのための可能性を示しています.

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Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
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