異なったHaemophilus influenzae型b結合ワクチンによって誘発された抗体の毒性および殺菌活性. ワクチン研究グループ (The Vaccine Study Group) は,ワクチンを研究している

Y Schlesinger1, D M Granoff

  • 1Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis, Mo.

JAMA
|March 18, 1992
PubMed
まとめ

新型Haemophilus influenzae型b (Hib) 結合ワクチンであるOligo-CRMとPRP-Tは,PRP-OMPCよりも高い抗体アビディティを誘発する. より高いアビディティ抗体は,補足媒介による殺菌活性においてより大きな効能を示しており,アビディティがワクチンの有効性にとって重要であることを示唆しています.

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