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Updated: Jul 18, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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哺乳類のスプライシングファクターU2AFのクローン化とドメイン構造

P D Zamore1, J G Patton, M R Green

  • 1Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138.

Nature
|February 13, 1992
PubMed
まとめ

研究者らは,U2 snRNP補助因子65 (U2AF65) の大きなサブユニットのための補完的なDNAクローンを分離し,発現した. この重要なスライシングファクタには,RNA結合とスライシングに特異なドメインが含まれています.

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