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Updated: Jul 19, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
22:00

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases

Published on: November 21, 2010

巨大膀の膜結合タンパク質:誘発収縮と成長

Victor A Seredyuk1, Fredric M Menger

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

Journal of the American Chemical Society
|September 30, 2004
PubMed
まとめ

フォスフォリピドとゼインタンパク質から成る巨大な膀は,硫酸塩二酸化ナトリウムを加えると縮小しますが,その二重層は自己治癒します. 巨大な膀の成長は,小型の膀との融合によって発生し,ゼインとドデシル硫酸ナトリウムによって促進されます.

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Protein Folding

Overview
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Mechanisms of Membrane-bending

The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
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Enlargement of the Plasma Membrane

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Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
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Protein Folding

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Protein Structure Is Critical to Its Biological Function
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Mechanisms of Membrane Domain Formation

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