関連する実験動画

Updated: May 11, 2026

Single-molecule Imaging of Gene Regulation In vivo Using Cotranslational Activation by Cleavage (CoTrAC)
11:31

Single-molecule Imaging of Gene Regulation In vivo Using Cotranslational Activation by Cleavage (CoTrAC)

Published on: March 15, 2013

CREBのコアクティベーターであるTORC2は,カルシウムとcAMPに敏感な偶然検出器として機能します

Robert A Screaton1, Michael D Conkright, Yoshiko Katoh

  • 1Peptide Biology Laboratories, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|September 30, 2004
PubMed
まとめ

栄養素と腸内ホルモンは,CREBを活性化することによって,臓の小島細胞機能を高めます. カルシヌーリンとSIK2を含む新しいシグナル伝達モジュールは,CREBの共同活性化剤であるTORC2を制御し,これらの経路を遺伝子発現に結びつける.

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