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関連する概念動画

Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
Visual System01:26

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...

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関連する実験動画

Updated: Jul 15, 2026

Live-imaging of the Drosophila Pupal Eye
09:54

Live-imaging of the Drosophila Pupal Eye

Published on: January 12, 2015

成人の主視野皮質における受容場動態.

C D Gilbert1, T N Wiesel

  • 1Rockefeller University, New York, New York 10021-6399.

Nature
|March 12, 1992
PubMed
まとめ

大人の脳は,網膜の損傷の後,視覚皮質を急速に再編成します. 入信信号だけでなく,皮質の可塑性が,この回復を駆動し,固有のシナプス変化を強調します.

科学分野:

  • 神経科学は神経科学である.
  • 神経可塑性とは
  • 視覚システム研究 視覚システム研究

背景:

  • 大人の脳は有意な可塑性を発揮し,変化した感覚入力に反応して皮質のトポグラフィを適応させます.
  • 以前の研究では,感覚的欠乏が時間とともに受容場サイズと皮質マップを修正することが示されています.

研究 の 目的:

  • 網膜病変による視覚入力除去後の即時および長期の皮質の再編成を調査する.
  • 視覚皮質の皮質回復と地形再編成の基礎となるメカニズムを決定する.

主な方法:

  • 成人の被験者における誘発的焦点双眼網膜損傷.
  • 損傷の前と直後に同じ皮質部位から記録された.
  • ゲニキュロコーティカルアフェレントの広がりを評価するための解剖学的研究を行いました.

主要な成果:

  • 網膜スコトーマの近くの皮質細胞の受容場サイズが,即座に大きく増加することが観察されました.
  • 以前に静止されていた皮質の領域における視覚活動の回復を数ヶ月以内に実証した.
  • lateral geniculate nucleusが大きな静かな領域を保持し, afferent spreadが皮質回復を説明するのに不十分であったことを発見しました.

さらに関連する動画

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin
07:51

Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin

Published on: December 30, 2025

関連する実験動画

Last Updated: Jul 15, 2026

Live-imaging of the Drosophila Pupal Eye
09:54

Live-imaging of the Drosophila Pupal Eye

Published on: January 12, 2015

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin
07:51

Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin

Published on: December 30, 2025

結論:

  • 網膜損傷後の視野皮質のトポグラフィック再編成は,主に皮質内の内在のシナプス変化によって引き起こされます.
  • 皮質内の長距離の水平接続は,この適応的可塑性において重要な役割を果たしている可能性が高い.
  • この発見は,アフェレント入力再構成のみに基づいた説明に異議を唱える.