Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Vaccinations01:51

Vaccinations

Overview
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Zebrafish Larvae as an Experimental Model of Cryptococcal Meningitis.

Methods in molecular biology (Clifton, N.J.)·2023
Same author

Technology of Informative Feature Selection for Immunosignature Analysis.

Sovremennye tekhnologii v meditsine·2021
Same author

First Report of Powdery Mildew in Greenhouse-Grown Tomatoes in New Jersey.

Plant disease·2019
Same author

An Assessment of Fungicide Benefits for the Control of Fungal Diseases of Processing Tomatoes in New York and New Jersey.

Plant disease·2019
Same author

Experiences of rosacea and its treatment: an interpretative phenomenological analysis.

The British journal of dermatology·2017
Same author

The evaluation of analgesia provided by epidural ketamine in dogs with chemically induced synovitis.

Veterinary anaesthesia and analgesia·2017

関連する実験動画

Updated: Jun 9, 2026

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
09:16

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors

Published on: October 30, 2016

遺伝子免疫は,免疫反応を誘発する簡単な方法である.

D C Tang1, M DeVit, S A Johnston

  • 1Department of Medicine, University of Texas, Dallas 75235-8573.

Nature
|March 12, 1992
PubMed
まとめ

研究者たちは,免疫反応を生み出すためのより速い方法である遺伝子免疫を開発しました. このテクニックでは,タンパク質を導入します.

科学分野:

  • 免疫学 免疫学とは
  • 分子生物学は分子生物学である.
  • バイオテクノロジー バイオテクノロジー

背景:

  • 免疫反応を起こすには,通常,外来タンパク質を浄化することが必要で,このプロセスは多くの場合時間がかかり,困難です.
  • 十分な量の純タンパク質を分離することは,免疫学的研究とワクチン開発における大きな障害です.

研究 の 目的:

  • タンパク質の浄化なしで免疫反応を誘発する代替方法を調査する.
  • 免疫を誘発するために動物の皮膚に直接的な遺伝子配送の可能性を探求する.

主な方法:

  • 手持ちのバイオリスティック・システムを活用して,DNAコーティングされた金製のマイクロプロジェクティルを発射した.
  • 外来タンパク質をコードする遺伝子をマウスの皮膚細胞に直接導入した.

主要な成果:

  • 遺伝子配送を用いて,異種タンパク質に対する免疫反応を成功裏に誘発した.
  • 遺伝子免疫が抗体を生成することを実証した.

結論:

  • 遺伝子免疫は,従来のタンパク質ベースの免疫に代わって,潜在的に時間と労力を節約する代替手段を提供します.

さらに関連する動画

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
11:50

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

関連する実験動画

Last Updated: Jun 9, 2026

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
09:16

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors

Published on: October 30, 2016

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
11:50

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

  • この新しいアプローチは,ワクチン接種と抗体生成のためのユニークな戦略を提供する可能性があります.