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Updated: Aug 11, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

マススペクトロメトリーによるクラスIのMHC分子HLA-A2.1に結合したペプチドの特徴づけ

D F Hunt1, R A Henderson, J Shabanowitz

  • 1Department of Chemistry, University of Virginia, Charlottesville 22903.

Science (New York, N.Y.)
|March 6, 1992
PubMed
まとめ

研究者は,高度な質量スペクトロメトリを使用して,HLA-A2.1分子に結合したユニークなペプチド構造を特定しました. この方法は,疾患に関連する細胞からのペプチドを効率的に分析し,T細胞の抗原プレゼンテーションを理解するのに役立ちます.

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