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Updated: Jul 9, 2026

HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL
07:18

HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL

Published on: April 11, 2011

変異細胞系からのHLA-A2.1関連ペプチド:抗原プレゼンテーションの第2の経路

R A Henderson1, H Michel, K Sakaguchi

  • 1Department of Microbiology, University of Virginia School of Medicine, Charlottesville 22908.

Science (New York, N.Y.)
|March 6, 1992
PubMed
まとめ

研究者らは,細胞が免疫認識のためにタンパク質を処理する新しい方法を発見しました. これは,エンドプラズマ網膜内のシグナルペプチドを分解して,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) クラスI分子を提示することを意味します.

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Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

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Cell-mediated Immune Responses

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Cells of the Adaptive Immune Response

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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

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Complete Antigens
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Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
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Antigen Processing Pathways

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MHC Class I: Presenting Endogenous...
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T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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