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Updated: Jul 7, 2026

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry

Published on: March 18, 2012

静電相互作用は,4-オクサロクロトナートタウトメラーゼにおけるアルグ39の触媒的貢献を支配する

Norman Metanis1, Ashraf Brik, Philip E Dawson

  • 1Department of Chemistry and Institute of Catalysis Science and Technology, Technion-Israel Institute of Technology, Technion City, Haifa 32000 Israel.

Journal of the American Chemical Society
|October 8, 2004
PubMed
まとめ

研究者は,アルギニンをシトルリンに置き換えて,4-OTの類似体を合成しました. 研究結果は,39位にあるアルギニンは,主に,水素結合ではなく,静電的に移行状態を安定させ,酵素触媒に影響を及ぼすことを示しています.

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