ベータ-アミノ酸ダイアミドに至る3つの成分凝縮:ベータ-ペプチドの類似体の収束組成

Jennifer M Oaksmith1, Ulf Peters, Bruce Ganem

  • 1Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301, USA.

まとめ

新しいパセリーニ凝縮反応により,機能化されたダイミドとベータペプチドが得られます. これらの化合物はプロテアゼ耐性であり,安定した構造を形成することができ,一部の抗生物質活性を示します.

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