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Updated: May 8, 2026

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ショットガン配列の組み立てと,ヒトゲノム内の最近のセグメンタル重複

Xinwei She1, Zhaoshi Jiang, Royden A Clark

  • 1Department of Genome Sciences, University of Washington School of Medicine, 1705 NE Pacific Street, Seattle, Washington 98195, USA.

Nature
|October 22, 2004
PubMed
まとめ

全ゲノムショットガン (WGS) 配列決定は,複雑なゲノムの中で,大きく,非常に類似した繰り返しを正確に組み立てるのに苦労します. これは,ゲノムサイズと遺伝子喪失の過小評価につながり,ゲノム構造の理解に影響を与えます.

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