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Updated: May 3, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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アレルギー反応におけるp110デルタフォスホイノシチド3キナーゼの重要な役割

Khaled Ali1, Antonio Bilancio, Matthew Thomas

  • 1Ludwig Institute for Cancer Research, 91 Riding House Street, London W1W 7BS, UK.

Nature
|October 22, 2004
PubMed
まとめ

マスト細胞におけるPI3K-p110deltaをターゲットにすることで,アレルギー反応を阻害することができます. マスト細胞におけるこの酵素の無活性化により,アレルギー反応が予防され,アレルギーの新たな治療標的となる.

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