Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Reaction Mechanisms03:06

Reaction Mechanisms

Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
Thermal and Photochemical Electrocyclic Reactions: Overview01:26

Thermal and Photochemical Electrocyclic Reactions: Overview

Electrocyclic reactions are reversible reactions. They involve an intramolecular cyclization or ring-opening of a conjugated polyene. Shown below are two examples of electrocyclic reactions. In the first reaction, the formation of the cyclic product is favored. In contrast, in the second reaction, ring-opening is favored due to the high ring strain associated with cyclobutene formation.
Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
Woodward–Hoffmann Selection Rules and Microscopic Reversibility01:34

Woodward–Hoffmann Selection Rules and Microscopic Reversibility

Electrocyclic reactions, cycloadditions, and sigmatropic rearrangements are concerted pericyclic reactions that proceed via a cyclic transition state. These reactions are stereospecific and regioselective. The stereochemistry of the products depends on the symmetry characteristics of the interacting orbitals and the reaction conditions. Accordingly, pericyclic reactions are classified as either symmetry-allowed or symmetry-forbidden. Woodward and Hoffmann presented the selection criteria for...
Membrane Asymmetry Regulating Transporters01:19

Membrane Asymmetry Regulating Transporters

Enzymes like flippase, floppase, and scramblase transfer phospholipids from one layer to another in the membrane, thereby affecting membrane asymmetry.
Flippase
Eukaryotic flippases are type-IV P-type ATPases or P4-ATPases belonging to P-type ATPase family proteins that are membrane-bound pumps involved in the ATP-mediated transport of ions and molecules across the membrane. Flippases flip specific phospholipids from the outer to the inner leaflet of a membrane. All P4-ATPases have one...
Reversible or Opposing Reactions01:26

Reversible or Opposing Reactions

Reversible or opposing reactions play a crucial role in understanding the dynamic nature of chemical processes. While kinetics focuses on how reactions proceed, thermodynamics emphasizes that most reactions do not reach completion. Instead, a reverse reaction starts occurring over time, and when its rate equals that of the forward reaction, a dynamic equilibrium is established.For example, consider a simple chemical process where A forms B reversibly. The rate constants for the forward and...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Structural Studies Provide Insight on the Fate of 1,5-Dithiacanes: Two Electron Reversible Oxidation versus Irreversible Oxidation.

The Journal of organic chemistry·2026
Same author

5,7-Dimethoxychroman-3-yl 4-methoxybenzoate Has a Unique Effect upon the Modulation of Mutant Cardiac Muscle Thin Filament Function and Dynamics due to Phosphorylation of Troponin I.

ACS pharmacology & translational science·2025
Same author

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations <i>in vitro</i>, <i>in vivo</i>, and <i>in silico</i>.

Frontiers in physiology·2024
Same author

Awakening a Molecular Mummy: The Inter-and Intramolecular Photochemistry of Pyromellitic Diimides with Alkyl Carboxylates.

Photochem·2024
Same author

Modulation of Structure and Dynamics of Cardiac Troponin by Phosphorylation and Mutations Revealed by Molecular Dynamics Simulations.

The journal of physical chemistry. B·2023
Same author

Kinetics and Mechanisms of Hydrothermal Dehydration of Cyclic 1,2- and 1,4-Diols.

The Journal of organic chemistry·2022

関連する実験動画

Updated: Jun 30, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

障壁のない電子転送結合の断片化反応.

Edward D Lorance1, Wolfgang H Kramer, Ian R Gould

  • 1Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287-1604, USA.

Journal of the American Chemical Society
|October 28, 2004
PubMed
まとめ

N-メトキシピリジルラジカルにおける超高速なN-O結合の断片化は,無障壁の電子移転によって起こります. 急速反応性のための分子設計原理が提案され,フェムト秒運動測定によって検証されました.

科学分野:

  • 化学動力学 化学動力学
  • フォトケミストリー フォトケミストリー
  • オーガニック化学 オーガニック化学

背景:

  • N-メトキシピリジル基は,N-メトキシピリジニウムを1電子減少させることで形成されます.
  • 超高速なN-O結合の断片化を調査することは,電子伝送反応を理解するために極めて重要です.

研究 の 目的:

  • N-メトキシピリジルラジカルにおける超高速なN-O結合の断片化を調査する.
  • 障壁のない電子移転誘発反応を予測するためのモデルを開発する.
  • 超高速反応性を促進する分子構造の特徴を特定する.

主な方法:

  • 潜在エネルギー表面の理論的モデリング.
  • フェムト秒の運動測定.
  • 反応力学に影響を与える電子的および幾何学的要因の分析.

主要な成果:

  • N-O結合の断片化の潜在エネルギー表面を記述するモデルが開発されました.
  • 超高速反応性のための分子構造的特徴が提案されました.
  • フェムトセカンドデータでは,p-メトキシ-N-メトキシピリジル基に対する運動的に障壁のない反応が確認されました.

さらに関連する動画

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors
10:44

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

関連する実験動画

Last Updated: Jun 30, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors
10:44

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

結論:

  • これらのラジカルにおけるN-O結合の断片化は,本質的に障壁のないプロセスである可能性があります.
  • 開発されたモデルは,超高速な化学変換のための分子設計に関する洞察を提供します.
  • フェムト秒運動は,急速な結合破裂の出来事を特徴付けるための強力なツールです.