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Updated: Jul 9, 2026

Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro
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Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro

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チャペロンを利用して,アミロイドβ結合の小分子阻害剤を生成する

Jason E Gestwicki1, Gerald R Crabtree, Isabella A Graef

  • 1Department of Pathology, Howard Hughes Medical Institute, Stanford University Medical School, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|October 30, 2004
PubMed
まとめ

研究者らは,神経変性疾患の重要な要因であるβ-アミロイド結合を抑制する新しい小分子を開発しました. この戦略は,タンパク質の塊に対する分子有効性を高めるために,シェーパーロンを使用することで,アルツハイマー病をターゲットにしています.

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Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

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