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ポリアラニンにおける新興キラル構造のシミュレーションされた進化

Vikas Nanda1, William F Degrado

  • 1Department of Biochemistry and Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. vikas@mail.med.upenn.edu

Journal of the American Chemical Society
|November 4, 2004
PubMed
まとめ

この研究では,シミュレートされた進化を用いて,モノマーキラリティがポリマー構造にどのように影響を与えるかを調査しています. 発見は,ヘテロキラルなモチーフと曲がったヘリックス構造を明らかにし,特定のステレオ化学的性質を持つ新しいヘテロポリマーを設計するための洞察を提供します.

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