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Updated: Jul 22, 2026

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
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型IIIの分泌針複合体の組み立てに関する構造的な洞察

Thomas C Marlovits1, Tomoko Kubori, Anand Sukhan

  • 1Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520-8024, USA.

Science (New York, N.Y.)
|November 6, 2004
PubMed
まとめ

研究者らは,サルモネラ・タイフィムリウムのタイプIII分泌システム (TTSS) の針複合体とその基礎の構造を明らかにした. 組み立てには,形状の変化とタンパク質の徴用が含まれ,TTSSが分泌中に標的を切り替える方法を説明する可能性がある.

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