mitra annulus-aorta 交差点から発生した左心房の低心拍です
Mario D Gonzalez1, Leonardo J Contreras, Monique R M Jongbloed
1Division of Cardiovascular Medicine, University of Florida College of Medicine, PO Box 100277, Gainesville, FL 32610-0277, USA. gonzamd@medicine.ufl.edu
Circulation
|November 10, 2004
まとめ
mitra annulus-aorta 交差点は,左心房低心拍の頻発源である. この発見は,アブレーションの課題を説明し,導電システムの残骸を原因として開発することを指摘する可能性があります.
科学分野:
- 心臓電気生理学 心臓電気生理学
- アリトモロジー アリトモロジー
- 胚の発達について
背景:
- mitra annulus-aorta (MA-Ao) 交差点は,左心房と前頭部ミトラを接続しています.
- この領域は,実験条件下で異常な電気活動を現しています.
研究 の 目的:
- MA-Ao交差点を左心房低心率 (LAT) の潜在的な源として調査する.
主な方法:
- LATを患った35人の患者を研究し,電図を用いて起源を特定しました.
- 誘発されたおよび特徴づけられた心拍のエピソード.
- 切除手術を行い,患者さんをフォローしました.
- マウス胚のMA-Ao領域を,伝導システムの発達のために調べました.
主要な成果:
- LATは患者の28%でMA-Ao交差点から発生した.
- タキカルディアエピソードは持続し,誘発可能であった.
- MA-Ao交差点での電図は,明確な特徴を示しました.
- アブラションにより,再発のない心拍動脈の除去に成功しました.
- マウス胚のMA-Ao領域に存在する特殊な伝導システムを開発.
結論:
- MA-Ao交差点は,LATの重要な源である.
- これは,右心房タヒカルディアと比較して,LATを消去する難しさを説明します.
- 胚伝導システムの残骸は,この領域のLATの基礎となる可能性があります.
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