タンパク質キナーゼCによる抑制を防ぐカリウムチャネルにおけるアミノ酸変異

A E Busch1, M D Varnum, R A North

  • 1Vollum Institute, Oregon Health Sciences University, Portland 97201.

Science (New York, N.Y.)
|March 27, 1992
PubMed
まとめ

タンパク質キナーゼCアクティベーターは,ネズミの腎臓のカリウムチャネルを阻害する. この抑制は,変異したチャネルを用いた実験で示されたように,Ser103におけるチャネルタンパク質の直接的リン酸化を経由して発生する.

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