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Updated: Aug 13, 2026

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain
11:29

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain

Published on: October 3, 2012

ヴァリン129を含むヒトプリオンタンパク質は,変異性CJD現象型の発現を防ぐ

Jonathan D F Wadsworth1, Emmanuel A Asante, Melanie Desbruslais

  • 1Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.

Science (New York, N.Y.)
|November 13, 2004
PubMed
まとめ

コドン129のヒトプリオンタンパク質 (PrP) ゲノタイプは,牛のスポンジ状脳症 (BSE) プリオン病に影響を与える. メチオニン129は,変異のクレッツフェルト・ヤコブ病 (vCJD) 現象型に必要であり,バリン129は耐性を授与する.

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