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関連する概念動画

Crossing Over01:34

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...
Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
Crossing Over01:30

Crossing Over

Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...

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関連する実験動画

Updated: Jul 5, 2026

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel&#8217;s Cartilage
06:40

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage

Published on: October 21, 2015

正しい選択をすること - 発達における長距離染色体相互作用

James R Broach1

  • 1Department of Molecular Biology, Princeton University, Princeton, NJ 08558, USA. jbroach@molbio.princeton.edu

Cell
|November 20, 2004
PubMed
まとめ
この要約は機械生成です。

Schizosaccharomyces pombeは,静かなDNAの位置と相互作用することによって,交配型を切り替えます. タンパク質複合体は,交配型ロシに広がり,交代のための正しいドナーをマークします.

さらに関連する動画

Multi-target Chromogenic Whole-mount In Situ Hybridization for Comparing Gene Expression Domains in Drosophila Embryos
10:17

Multi-target Chromogenic Whole-mount In Situ Hybridization for Comparing Gene Expression Domains in Drosophila Embryos

Published on: January 31, 2016

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

関連する実験動画

Last Updated: Jul 5, 2026

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel&#8217;s Cartilage
06:40

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage

Published on: October 21, 2015

Multi-target Chromogenic Whole-mount In Situ Hybridization for Comparing Gene Expression Domains in Drosophila Embryos
10:17

Multi-target Chromogenic Whole-mount In Situ Hybridization for Comparing Gene Expression Domains in Drosophila Embryos

Published on: January 31, 2016

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

科学分野:

  • 分子生物学は分子生物学である.
  • 遺伝学 遺伝学とは
  • 細胞生物学 細胞生物学

背景:

  • Schizosaccharomyces pombeは,世代ごとに交配型を切り替えるユニークな能力を発揮しています.
  • この交配型スイッチングは,発現部位と静かなドナー部位との相互作用を伴う.

研究 の 目的:

  • Schizosaccharomyces pombeが,交配型切り替えのために適切な静かなドナーロクスを選択するメカニズムを解明する.
  • この選択過程におけるタンパク質複合体とヘテロクロマチンの役割を理解する.

主な方法:

  • 交配型の発現部位と静かなドナー部位との相互作用を調査した.
  • タンパク質複合体の交配型依存およびヘテロクロマチン依存の拡散の役割を分析した.

主要な成果:

  • タンパク質複合体が正しいドナーの位置をマークすることに関与することを示した.
  • この複合体の拡散は交配型とヘテロクロマチンに依存することを示した.
  • この複合体は,交配型の切り替えのために適切なドナーロクスの選択を容易にする.

結論:

  • Schizosaccharomyces pombeのドナー・ロカス選択は,特定のタンパク質複合体の交配型およびヘテロクロマチン依存の拡散によって媒介されます.
  • このメカニズムは,この分裂酵母における正確かつタイムリーな交配型切り替えを保証します.