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Updated: Jul 12, 2026

Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates
07:42

Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates

Published on: October 18, 2018

カリウムチャネル開拓剤の抗リズム効果は,遅れた再極化に関連するリズム異常に起因する

L Carlsson1, C Abrahamsson, L Drews

  • 1Department of Cardiovascular Pharmacology, Astra Hässle AB, Mölndal, Sweden.

Circulation
|April 1, 1992
PubMed
まとめ

カリウムチャネル開き薬ピナシジルおよびその類似品であるP1075およびP1188は,ウサギにおける薬剤誘発の多型心室タキアリズム (PVTs) を減少させた. これらの化合物はまた,早期のデポラライゼーション後を廃止し,活性化を誘発し,特定の心律不整症の治療の可能性を示唆しました.

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