セラジン-1による腫瘍的および酸化的ストレスに対する細胞応答の調節

Chaowei Wu1, Irene Miloslavskaya, Silvia Demontis

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

Nature
|December 4, 2004
PubMed
まとめ

セラジン-1は,腫瘍抑制剤p53.3を安定させることで,腫瘍原発性および酸化性ストレスに対する細胞反応を統合します. このタンパク質は,Ras誘発の老化バイパスを防止し,がん細胞の変容を抑制します.

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