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Updated: Jul 12, 2026

Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds
18:25

Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds

Published on: August 25, 2013

Smoothenedのヘッジホッグシグナル伝達活動は,タンパク質キナーゼAとカゼインキナーゼIによるリン酸化を必要とする

Jianhang Jia1, Chao Tong, Bing Wang

  • 1Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. jin.jiang@utsouthwestern.edu

Nature
|December 24, 2004
PubMed
まとめ

タンパク質キナーゼA (PKA) とカゼインキナーゼI (CKI) は,スモートヘッド (Smo) をリン酸化することによってヘッジホッグ (Hh) 信号を調節する. このリン酸化は,動物の発達中にSmo細胞表面の蓄積と経路の活動を制御する.

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Detection of Protein S-Acylation using Acyl-Resin Assisted Capture08:31

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