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Updated: Jun 23, 2026

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
10:00

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling

Published on: October 28, 2014

TORは,PKAとフォークヘッド転写因子FHL1を介してリボソームタンパク質の遺伝子発現を調節する

Dietmar E Martin1, Alexandre Soulard, Michael N Hall

  • 1Division of Biochemistry, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland.

Cell
|December 29, 2004
PubMed
まとめ

ラパミシン (TOR) 経路の標的は,タンパク質キナーゼA (PKA) を通してリボソーム生体生成を調節する. この研究では,フォークヘッド型転写因子1 (FHL1) およびその共因子IFH1およびCRF1が,この栄養素に敏感なシグナル伝達メカニズムにおいて重要な役割を果たしていることを特定しています.

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Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle

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Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster04:59

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