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Updated: Jul 30, 2026

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices
10:04

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices

Published on: October 29, 2012

物理化学を用いて,ニコチンアセチルコリン受容体におけるニコチンアゴニストとコリンアゴニストを区別する

Amanda L Cashin1, E James Petersson, Henry A Lester

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|January 6, 2005
PubMed
まとめ

非自然なアミノ酸変異により,アセチルコリン (ACh),ニコチン,エピバチチドンがニコチン性アセチルコリン受容体に結合する方法が明らかになりました. 異なるアゴニストは,強力な受容体結合のために,カチオン-ピと水素結合を含む特定の相互作用を使用します.

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Localization of Plasma Membrane and Intracellular Neuronal Nicotinic Acetylcholine Receptors Using Quantitative Imaging in Mammalian Cells09:06

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