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Updated: Jul 19, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

人間におけるX染色体の位置の非非活性化

L J Shapiro, T Mohandas, R Weiss

    Science (New York, N.Y.)
    |June 15, 1979
    PubMed
    まとめ

    X-リンクされたイチオシスにおけるステロイドスルファターゼ遺伝子は,X-不活性化から逃れるように見える. この発見は,この遺伝子は,リンクされたXgaロカスと同様に,ヒトのX染色体不活性化という典型的なプロセスを受けていないことを示唆している.

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    X-Inactivation01:58

    X-Inactivation

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    Heterochromatin02:38

    Heterochromatin

    The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
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