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Updated: May 5, 2026

RNAi Interference by dsRNA Injection into Drosophila Embryos
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ドロソフィラのトリメア型Gタンパク質依存のカサカサシグナル伝達

Vladimir L Katanaev1, Romina Ponzielli, Michel Sémériva

  • 1Department of Genetics and Development, Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 701 West 168 Street, New York, NY 10032, USA.

Cell
|January 18, 2005
PubMed
まとめ

この研究では,Galpha (o) サブユニット (Go) が,ドロソフィラのFrizzled (Fz) 受容体の重要なトランスデューサーとして作用し,Wntと平面の極性シグナル伝達経路の両方を媒介することを明らかにしました. Goは,Fz信号伝導に不可欠であり,受容体を下流の細胞応答と結びつける.

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