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Updated: Jul 6, 2026

Pull-down of Calmodulin-binding Proteins
07:51

Pull-down of Calmodulin-binding Proteins

Published on: January 23, 2012

カルモジュリン主鎖のダイナミクスの変化は,交互に相関するNMRリラクゼーション測定によって明らかにされたリガンド結合時に発生する

Tianzhi Wang1, Kendra King Frederick, Tatyana I Igumenova

  • 1Biophysics Research Division, Department of Biological Chemistry, The University of Michigan, 930 N. University Avenue, Ann Arbor, Michigan 48109-1055, USA.

Journal of the American Chemical Society
|January 20, 2005
PubMed
まとめ

核磁気緩和の研究は,タンパク質の骨幹のダイナミクスにおける微妙な変化を明らかにしています. 新しいNMR方法は,リガンド結合時に主鎖のエントロピーの有意な損失を示し,サイドチェーンダイナミクスの中間である.

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