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Updated: Jul 21, 2026

Assaying the Kinase Activity of LRRK2 in vitro
06:09

Assaying the Kinase Activity of LRRK2 in vitro

Published on: January 18, 2012

発症頻度の高いLRRK2遺伝子変異は,自己相性多発性パーキンソン病と関連している

Alessio Di Fonzo1, Christan F Rohé, Joaquim Ferreira

  • 1Department of Clinical Genetics, Erasmus MC Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands.

Lancet (London, England)
|February 1, 2005
PubMed
まとめ

Leucine-Rich Repeat Kinase 2 (LRRK2) 遺伝子であるGly2019Serの一般的な突然変異は,自己相支配的なパーキンソン病に関連しています. この発見は,多様な集団における神経変性におけるLRRK2の役割を確認しています.

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