関連する実験動画

Updated: Jul 21, 2026

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
08:40

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

Published on: April 6, 2012

マイクロアレイ分析は,一部のマイクロRNAが多数の標的mRNAをダウンレギュレーションすることを示しています

Lee P Lim1, Nelson C Lau, Philip Garrett-Engele

  • 1Rosetta Inpharmatics, Merck and Co, 401 Terry Avenue N, Seattle, Washington 98109, USA. lee_lim@merck.com

Nature
|February 3, 2005
PubMed
まとめ

マイクロRNA (miRNA) は遺伝子発現を調節する. ヒト細胞に特定のmiRNAを導入することで,遺伝子発現プロファイルが変化し,多数の標的メッセンジャーRNAがダウンレギュレーションされ,より広範な規制的役割が明らかになった.

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Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs11:00

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs

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