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アトルバスタチンによる短期治療は,高コレステロール血症患者の血小板CD40リンガンドとトロンビン生成を減少させます

Valerio Sanguigni1, Pasquale Pignatelli, Luisa Lenti

  • 1Department of Experimental Medicine and Pathology, University of Rome La Sapienza, Rome, Italy.

Circulation
|February 3, 2005
PubMed
まとめ

高コレステロール血症では,溶性CD40L (sCD40L) と血小板CD40Lの上昇は,血栓生成の増加と関連しています. アトルバスタチン治療はこれらのマーカーを減少させ,コレステロールの減少とは関係のない直接的な抗血栓効果を示した.

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