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Updated: May 4, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

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原生AMPA受容体複合体の構造と異なる構成状態

Terunaga Nakagawa1, Yifan Cheng, Elizabeth Ramm

  • 1The Picower Center for Learning and Memory, RIKEN-MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Nature
|February 4, 2005
PubMed
まとめ

この研究は,ネズミの脳からのネイティブAMPA受容体 (アルファ-アミノ-3-ヒドロキシ-5-メチル-4-イソクサゾールプロピオン酸受容体) の3D構造を明らかにしています. 研究結果は,これらの重要な脳受容体が様々な形状に存在し,シナプス伝達と神経疾患の理解に影響を与えていることを示しています.

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