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Updated: Jul 10, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
08:35

Examining BCL-2 Family Function with Large Unilamellar Vesicles

Published on: October 5, 2012

bcl-2タンパク質のパラログ選択リガンドである.

Anja C Gemperli1, Stacey E Rutledge, Abby Maranda

  • 1Departments of Chemistry and Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.

Journal of the American Chemical Society
|February 11, 2005
PubMed
まとめ

研究者は,PPBH3-5とPPBH3-6というミニチュアタンパク質を設計して,Bcl-XLの上にBcl-2タンパク質を選択的に結合させました. これらの新しい非自然なリガンドは,特定のタンパク質とタンパク質の相互作用を抑制するための新しいツールを提供します.

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