冠動脈カルシフィケーションと冠外動脈動脈硬化との関連性 症状のない高コレステロール血症の男性における冠外動脈動脈硬化. PCV METRAグループは,PCV METRAグループに所属しています
J L Megnien1, V Sene, S Jeannin
1Centre de Médecine Préventive Cardio-vasculaire, INSERM U 28, Paris, France.
Circulation
|May 1, 1992
まとめ
高コレステロールの患者では,冠動脈のカルシフィケーションは,他の動脈のプラークと強く関連しています. これらの冠動脈外血管のエコー撮影は,無症状の個体において冠動脈疾患を検診するのに役立ちます.
科学分野:
- 心血管医学は,心臓血管医学である.
- 放射線学 放射線学
- メディカルイマージング (医学イメージング)
背景:
- 症状のない高コレステロール血症の患者における冠動脈結石化および冠動脈外プラークの有病率を調査した.
- 冠動脈結石化と冠外動脈硬化負荷の関連性を評価した.
研究 の 目的:
- 高コレステロール血症の男性における冠動脈カルシフィケーションと冠動脈外プラークの関係を見極めるため.
- 冠動脈外血管評価が冠動脈動脈硬化症のスクリーニングに役立つことを評価する.
主な方法:
- 冠動脈カルシウムスコアを測定するために超高速コンピューティングトモグラフィー (CT) を利用しました.
- 111人の高コレステロール血症の男性で頸動脈,大動脈,股関節のプラークのエコー検査を行った.
- 冠動脈カルシフィケーション (存在/欠如,カルシウムスコア) と冠動脈外プラークの存在との関連を分析した.
主要な成果:
- 患者の65%が冠動脈の結石化,72%が冠動脈外プラークを発症した.
- 冠動脈の結石化は,大動脈と股関節のプラーク,および病んでいる冠外部の部位の数と有意に関連していました.
- 冠動脈カルシウム値の上昇は,頸動脈,大動脈,股関節のプラークの存在,および病気の部位の数と相関していた.
- 2つまたは3つの病んだ冠外線部位の存在は,78%のパワーで冠外線カルシフィケーションを予測しました.
- 冠動脈カルシウムスコアは,年齢とトリグリセリド値と相関しています.
結論:
- 冠動脈カルシウムと冠動脈外プラークの間には強い関係がある.
- 冠外血管のエコーグラフィは,高リスクで無症状の個体における冠動脈動脈硬化症の貴重なスクリーニングツールとして役立つ可能性があります.
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