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Updated: May 4, 2026

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フォスフォリファースCgamma1は,分子間PHドメインを通してTRPC3の表面発現を制御する

Damian B van Rossum1, Randen L Patterson, Sumit Sharma

  • 1Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Nature
|March 4, 2005
PubMed
まとめ

科学者たちは,イオンチャネルと脂質結合を含む新しいシグナル伝達機構を発見しました. PLC-gamma1の部分プレックストリンホモロジー (PH) ドメインはTRPC3チャネルと相互作用し,カルシウムの入り込みと細胞表面発現を調節する.

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