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Updated: Jul 16, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
11:27

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OSBPは,ERK1/2活性化を制御するコレステロール調節された脚本タンパク質です

Ping-Yuan Wang1, Jian Weng, Richard G W Anderson

  • 1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9039, USA.

Science (New York, N.Y.)
|March 5, 2005
PubMed
まとめ

オキシステロール結合タンパク質 (OSBP) によって結ばれるコレステロールは,ERKシグナル伝達経路を調節するフォスファターゼ複合体を形成します. この複合体は,コレステロールレベルが低下すると分解され,シグナル伝達が増加します.

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