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関連する概念動画

Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
Unrenewable Cells00:50

Unrenewable Cells

In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
Auditory Perception01:17

Auditory Perception

The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
Perceiving Loudness, Pitch, and Location01:21

Perceiving Loudness, Pitch, and Location

The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Piaget's Stage 1 of Cognitive Development01:14

Piaget's Stage 1 of Cognitive Development

The sensorimotor stage, the initial phase of Jean Piaget's theory of cognitive development, spans the first two years of a child's life. During this period, infants actively engage with their surroundings, building cognitive awareness through direct interaction with the world. This interaction is primarily based on sensory perception and motor actions, allowing infants to gradually understand basic physical properties and predict how objects interact within their environment.
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関連する実験動画

Updated: Jul 20, 2026

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

子どもにおける感覚神経性聴覚障害

Richard J H Smith1, James F Bale, Karl R White

  • 1Molecular Otolaryngology Research Laboratories, Department of Otolaryngology, University of Iowa, Iowa City, IA, USA. Richard-smith@uiowa.edu

Lancet (London, England)
|March 9, 2005
PubMed
まとめ

発達途上国では,よりよいケアとワクチンのおかげで,子供時代の聴覚障害は減少しています. しかし,特にGJB2遺伝子による遺伝性聴覚障害は増加しており,遺伝カウンセリングと健康教育を世界中で必要としています.

科学分野:

  • 遺伝学 遺伝学とは
  • 公衆衛生は公衆衛生である.
  • オーディオロジー オーディオロジー

背景:

  • 発達途上国では30~40年以上にわたり,子供における既得性感覚神経性聴覚障害 (SNHL) の発生率は低下しています.
  • 新生児ケアの改善と広範囲にわたる予防接種プログラムは,この減少の重要な要因です.
  • この減少は,遺伝型SNHLの相対的な増加と並行しており,GJB2遺伝子が重要な役割を果たしています.

研究 の 目的:

  • 幼児期における難聴の状況の変化を分析し,既得原因と遺伝原因に焦点を当てました.
  • 遺伝的要因,特にGJB2遺伝子がSNHLの評価とケアに与える影響を強調する.
  • 発展途上国における傾向と,発展途上国における傾向を比較し,介入策を提案する.

主な方法:

  • 子どもの感覚神経性聴力障害の流行病学的傾向を数十年にわたってレビューする.
  • GJB2遺伝子を含む遺伝的要因が,SNHLの全体的な負担に与える寄与の分析.
  • 開発途上国と開発途上国におけるSNHLの流行の比較評価,血縁関係や貧困などの要因を考慮する.

主要な成果:

  • 先進国では,得られたSNHLは減少しているが,遺伝されたSNHLは相対的に増加している.

さらに関連する動画

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention
04:32

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention

Published on: December 20, 2024

関連する実験動画

Last Updated: Jul 20, 2026

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention
04:32

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention

Published on: December 20, 2024

  • GJB2遺伝子のSNHLへの貢献は,遺伝的評価において有意である.
  • 発展途上国,特に血縁関係や貧困が強い国では,既得性および遺伝性SNHLの比率が高く,減少は観察されていません.
  • 結論:

    • ターゲットを絞った遺伝カウンセリングと健康教育は,発展途上国における遺伝性SNHLの減少に不可欠です.
    • 予防可能な感染症に対するワクチン接種プログラムを実施することで,獲得SNHL率を低下させることができます.
    • ワクチン接種を通じて感染を予防することは,生存者のSNHLのような永続的な障害を減らすという二次的な利点を提供します.