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Updated: Jul 6, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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p38 ミトゲン活性化タンパク質キナーゼは,内皮原始細胞をダウンレギュレーションします

Florian H Seeger1, Judith Haendeler, Dirk H Walter

  • 1Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Theodor-Stern-Kai 7, Frankfurt, Germany.

Circulation
|March 9, 2005
PubMed
まとめ

p38 グルコースとTNF-αによるMAPキナーゼの活性化により,内皮原始細胞 (EPC) 数は減少する. SB203580でp38キナーゼを阻害すると,EPCが増加し,新血管化が改善され,細胞治療の可能性がある.

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