白人,黒人,ヒスパニック系の白血性脳卒中のサブタイプ発生率:北マンハッタン研究
Halina White1, Bernadette Boden-Albala, Cuiling Wang
1Department of Neurology, College of Physicians and Surgeons, USA.
Circulation
|March 17, 2005
まとめ
黒人およびヒスパニック系の人々は,すべての脳卒中サブタイプにおける増加率に起因して,白人よりも高度の缺血性脳卒中発生率を持っています. マンハッタンの北部の住民を対象としたこの研究では,脳卒中リスクにおける有意な人種・民族の格差が強調されています.
科学分野:
- 神経学 神経学とは
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
背景:
- 脳卒中の発生率は,白人の集団と比較して黒人の集団では著しく高く,ヒスパニック系個人に限られたデータしか利用できません.
- 脳卒中のリスクにおける人種・民族の違いを理解するには,サブタイプ特異的な缺血性脳卒中の発生率を調べる必要があります.
研究 の 目的:
- 一つのコミュニティに居住する白人,黒人,ヒスパニックの集団の中で,不全性脳卒中のサブタイプの発生率を決定し,比較する.
- 脳卒中のリスクにおける観察された人種・民族の格差に対する異なる缺血性脳卒中のサブタイプの貢献を明らかにする.
主な方法:
- マンハッタン北部の4年間の期間 (1993年7月 - 1997年6月) にわたって最初の不血性脳卒中の症例を特定するために,包括的な脳卒中監視システムを利用した人口ベースの研究.
- 低血圧性脳卒中のサブタイプは,改訂された国立神経疾患研究所と脳卒中 (NINDS) スキムを使用して分類されました.
- 年齢調整された,人種特有の罹患率と脳卒中サブタイプの相対率を計算し,人種・民族のグループで比較した.
主要な成果:
- 年齢調整による初回の脳卒中発生率は10万人あたり,白人では88人,ヒスパニックでは149人,黒人では191人でした.
- 白人と比較すると,黒人は脳内動脈硬化性脳卒中 (5.85),脳外動脈硬化性脳卒中 (3.18),および性脳卒中 (3.09) の相対的な割合が著しく高かった.
- また,ヒスパニック系は,白人と比べて,頭蓋内動脈硬化性脳卒中 (5.00) と内脳卒中 (2.32) の相対的な割合も高かった.
結論:
- 白人集団と比較して黒人およびヒスパニック集団で観察された高発性不全性脳卒中は,すべての特定された不全性脳卒中サブタイプにおけるより高い割合に起因する.
- これらの発見は,様々なエチオロギー的なサブタイプの影響を受けた脳卒中リスクにおける有意な人種的-民族的格差を強調しています.
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